Public beta© 2026 Adaptrex, LLC
Public beta© 2026 Adaptrex, LLC
Federal grant · project grant (b)
Single Cell Tri-omics: High Coverage Simultaneous Profiling of Dna, Rna, and Proteins in Single Cells - Abstract Alzheimer's Disease, a Devastating Neurologic Disorder, Accounts for 60-80% of All Dementias, Making the Development of New Technologies for Studying the Disease Crucial. Fluid Discovery Aims to Advance Single-cell Proteomics With a Groundbreaking Product Called Self-assembled Partitioning Proteomics (sap-pm), Which Will Quantify Thousands of Proteins in Hundreds of Thousands of Individual Cells and Can Be Multiplexed With Single Cell Dna and Rna Sequencing. Building on Cutting-edge Work in Microfluidics, Biophysics, and Genomics, Sap- PM Offers a Unique, Rapid, and Cost-effective Method to Overcome Limitations in Protein Coverage and Sensitivity Found in Current Technologies. the Project Comprises Two Aims: (1) Develop Sap-pm for Sensitive, Thousand-plex Analysis of Proteins at the Single Cell Level, and (2) Expand the Capability of Sap-pm to Analyze Brain Nuclei and Simultaneously Capture Mrna, Facilitating Valuable Insights From Primary Human Tissues to Improve Human Health.
Committed
$268,142
Paid out
$227.7K
85%
Committed, not yet paid
$40.5K
15%
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