Tetraimaging LLC

Novel Tetrahedron Beam CT for Point-of-care Imaging in Ear, Nose and Throat Imaging - Abstract Point-of-care Imaging Is Highly Desired in Otolaryngologic Clinics for the Diagnosis of Ear, Nose and Throat (ENT) Diseases Including Cancers. Due to Limited Image Quality, Current Cone-beam CT (CBCT) Products Act Not as a Substitute But Rather as a Complement to Diagnostic Multi-slice CT (MSCT) in Maxillofacial and Ent Imaging. the Emerging Multi-source X-ray Source Technology Suggests New Designs of CT Systems That May Have Faster Imaging Speed, Improved Image Quality, Reduced Radiation Exposure, and Compact Geometries. Tetrahedron Beam Computed Tomography (TBCT) Is a Compact Volumetric CT Based on Linear Array Multi- Pixel X-ray Sources Which Can Produce Diagnostic-quality Volumetric Images But in a Much More Compact Geometry Than CBCT. During Phase I Study, We Successfully Developed a Benchtop Ent-tbct System Using a Multi-pixel Thermionic Emission X-ray (MPTEX) Source Developed In-house and a State-of-art Commercial Photon-counting Detector (PCD), and Demonstrated the Superior Image Quality That TBCT Can Achieve. During the Phase Ii Study, We Will Further Refine the Mptex Source and Develop a Clinical Prototype System. to Achieve This Goal, We Propose to Perform Studies to Achieve the Following Specific Aims (sa): Sa 1: to Develop a Rotatable Sealed Mptex Source; Sa 2: to Develop a Clinical Ent-tbct Prototype on a Rotating Gantry; and Sa 3: to Develop Advanced Image Reconstruction Algorithm and Perform Benchmark Imaging Studies. the Outcome of This Research Will Be a Highly Effective Point-of-care Diagnostic Imaging Modality for Otolaryngologic Clinics. Future Commercialization of the Ent-tbct System Will Improve the Quality and Efficacy by Supporting Prompt Diagnosis and Treatment of Ent Cancers and Other Diseases.