Midwestern University

The Proposed Project Is a Highly Integrated Multidisciplined Collaborative Effort by Faculty Who Are Committed to Advancing Basic and Clinical Research in Animal Health and Disease That Will Further the Principle of One Health. the Objective of This Project Is to Increase Animal Health and Disease Research Activities at the Midwestern University College of Veterinary Medicine in Line With the Principles of One Health. One Health Issues Include Zoonotic Diseases, Antimicrobial Resistance, Vector-borne Diseases, and Other Heath Threats. to Meet These Goals, We Will Address the Following Aims. 1). Investigate the Epidemiology and Pathogenesis of Animal and Human Infectious Diseases Prevalent in the State and Nation, Including Cryptosporidiosis, Rift Valley Fever, Canine Distemper, and Foot and Mouth Disease. 2). to Facilitate Studies on the Immunobiology and Pathology of Animal and Human Infections, in Vitro, Ex Vivo and in Vivo Assays Will Be Developed to Examine the Effect of These Infections in Host Immune Response and Disease. 3). Develop Intervention Approaches to Treat And/or Prevent Animal and Human Diseases, Employing Animal Models of Infection and Disease and State-of-art Facilities. Successful Completion of This Project Will Facilitate Our Understanding of the Requirements for Attaining the Long-term Goal of Optimal Health for Animals, People, and the Environment.