Federal award · other reimbursable, contingent, intangible, or indirect financial assistance
Mechanisms of Dry Bean Mediated Anti-obesogenic Activity - (1) Determine How Fat Deposition Is Partitioned in Bean-fed Versus Control-fed Mice That Are Provided Isocaloric Amounts of Diet. (2) Evaluate the Extent to Which Bean Consumption Affects Caloric Uptake and the Fraction of Ingested Energy That Is Excreted in the Feces, Using a Mouse Model. (3) Use Indirect Calorimetry to Determine How Bean Consumption Affects Respiratory Quotient And/or Energy Expenditure. (4) Examine the Role of Bean Consumption on the Activation of Amp-activated Protein Kinase and Its Effect on Lipid Metabolism. (5) Examine Functional Changes in the Gut Microbiome Mediated by Bean Consumption, Focusing on Bile Salt Hydrolase Activity and How This Affects Farnesoid X Receptor (FXR) Activity in the Ileum.
Committed
$465,337
Paid out
$418.4K
90%
Committed, not yet paid
$46.9K
10%
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