Public beta© 2026 Adaptrex, LLC
Public beta© 2026 Adaptrex, LLC
Federal award · other reimbursable, contingent, intangible, or indirect financial assistance
Food Security Model Development: Improving Income Response and Food Production Projections. - Utilizing the First Generation Adenovirus Vectored Foot-and-mouth Disease Virus Vaccine (AD5-FMD) in Combination With Adenovirus Vectored Porcine Interferon Alpha (AD5-POIFNALPHA), It Has Been Demonstrated That Swine Can Be Protected as Early as One Day and for Approximately Five Days Post Vaccination and There Is an Enhancement of the Long-term Level of Immunity. Utilization of Pattern Recognition Receptor (PRR) Agonists, Such as Polyic, Alone or in Combination With Interferons (ifns),can Also Protect Swine Against FMDV. Preliminary Studies Have Shown That Utilization of AD5-FMD Vaccine in Combination With Polyiclc Has Also Improved Vaccine Potency. This Collaborative Research Project Seeks to Construct a Modified AD5 Vector to Fully Protect Swine Against FMD, Increasing the Stability of Transgene Expression With the Ability to Express Multiple Transgenes or Inducers of Innate Immunity From the Same Vector.
Committed
$42,087
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